Interaction information

References

1 reference(s)

PubMed

LONG, R M, et al., EMBO J. 2000 Dec;19(23):6592-601

PMID

11101531

Title

She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA.

Authors

LONG, R M, et al.

LONG, R M
GU, W
LORIMER, E
SINGER, R H
CHARTRAND, P

Citation

EMBO J. 2000 Dec;19(23):6592-601

Term ID

GO:0003729

Name

mRNA binding

Namespace

molecular_function

Definition

Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA) or messenger RNA (mRNA).

Is-a

1 item(s)

GO:0003723: RNA binding

Processes

3 process(s)

GO:0007029

[RCA] endoplasmic reticulum organization

Evidence

Term ID

GO:0007029

Name

endoplasmic reticulum organization

Namespace

biological_process

Definition

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.

Synonyms

5 synonym(s)

endoplasmic reticulum morphology
endoplasmic reticulum organisation (GOC:curators)
endoplasmic reticulum organization and biogenesis (GOC:mah)
ER organisation (GOC:curators)
ER organization and biogenesis (GOC:mah)

Is-a

1 item(s)

GO:0006996: organelle organization

GO:0007533

[IMP] mating type switching

Evidence

References

1 reference(s)

PubMed

JANSEN, R P, et al., Cell 1996 Mar;84(5):687-97

PMID

8625407

Title

Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

Authors

JANSEN, R P, et al.

JANSEN, R P
DOWZER, C
MICHAELIS, C
GALOVA, M
NASMYTH, K

Citation

Cell 1996 Mar;84(5):687-97

Term ID

GO:0007533

Name

mating type switching

Namespace

biological_process

Definition

The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.

Synonyms

1 synonym(s)

mating type switching and recombination

Is-a

3 item(s)

GO:0006259: DNA metabolic process
GO:0007531: mating type determination
GO:0022413: reproductive process in single-celled organism

GO:0008298

[IDA] intracellular mRNA localization

Evidence

References

1 reference(s)

PubMed

BöHL, F, et al., EMBO J. 2000 Oct;19(20):5514-24

PMID

11032818

Title

She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p.

Authors

BöHL, F, et al.

BöHL, F
KRUSE, C
FRANK, A
FERRING, D
JANSEN, R P

Citation

EMBO J. 2000 Oct;19(20):5514-24

Term ID

GO:0008298

Name

intracellular mRNA localization

Namespace

biological_process

Definition

Any process by which mRNA is transported to, or maintained in, a specific location within the cell.

Synonyms

4 synonym(s)

establishment and maintenance of intracellular RNA localization
intracellular mRNA positioning
mRNA localization, intracellular
mRNA positioning, intracellular

Is-a

2 item(s)

GO:0006403: RNA localization
GO:0070727: cellular macromolecule localization

Components

2 component(s)

GO:0005737

[IDA] cytoplasm

Evidence

References

1 reference(s)

PubMed

JANSEN, R P, et al., Cell 1996 Mar;84(5):687-97

PMID

8625407

Title

Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

Authors

JANSEN, R P, et al.

JANSEN, R P
DOWZER, C
MICHAELIS, C
GALOVA, M
NASMYTH, K

Citation

Cell 1996 Mar;84(5):687-97

Term ID

GO:0005737

Name

cytoplasm

Namespace

cellular_component

Definition

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

Is-a

1 item(s)

GO:0044424: intracellular part

GO:0005934

[IDA] cellular bud tip

Evidence

References

1 reference(s)

PubMed

BöHL, F, et al., EMBO J. 2000 Oct;19(20):5514-24

PMID

11032818

Title

She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p.

Authors

BöHL, F, et al.

BöHL, F
KRUSE, C
FRANK, A
FERRING, D
JANSEN, R P

Citation

EMBO J. 2000 Oct;19(20):5514-24

Term ID

GO:0005934

Name

cellular bud tip

Namespace

cellular_component

Definition

The end of a cellular bud distal to the site of attachment to the mother cell.

Is-a

1 item(s)

GO:0030427: site of polarized growth

Origin

Saccharomyces cerevisiae S288c

NCBI Taxonomy ID: 559292
Name: Saccharomyces cerevisiae S288c

Cross references

9 item(s)

RefSeq: NP_012792
Entrez Gene: 853728
SGD: S000001613
UniProt: P36068
BioGRID: 34005
GenBank Nucleotide: 296146251
GenBank Protein: DAA09031
GenBank Protein: 6322719
GenBank Protein: 285813134

Experimental roles

1 role(s)

Role 1

bait

Term ID

MI:0496

Name

bait

Definition

Molecule experimentally treated to capture its interacting partners.

Is-a

1 item(s)

MI:0495: experimental role

Identification methods

1 identification method(s)

Method 1

predetermined participant

Term ID

MI:0396

Name

predetermined participant

Definition

Molecule whose sequence identity is not checked and has been assumed from external or previous experimental evidence(s).

Synonyms

1 synonym(s)

predetermined (PSI-MI-short)

Is-a

1 item(s)

MI:0661: experimental participant identification

RNA information

Short label

CDC42

Gene

CDC42 (Cdc42p)

GeneID

850930

Official symbol

CDC42

Description

Cdc42p

Other names

1 designation(s)

Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins

Ontologies

38 ontology(s)

Functions

4 function(s)

GO:0000166

[IEA] nucleotide binding

Evidence

Term ID

GO:0000166

Name

nucleotide binding

Namespace

molecular_function

Definition

Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose moiety.

Is-a

1 item(s)

GO:0005488: binding

GO:0003924

[IDA] GTPase activity

Evidence

References

1 reference(s)

PubMed

ROUMANIE, O, et al., FEBS Lett. 2001 Oct;506(2):149-56

PMID

11591390

Title

Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae.

Authors

ROUMANIE, O, et al.

ROUMANIE, O
WEINACHTER, C
LARRIEU, I
CROUZET, M
DOIGNON, F

Citation

FEBS Lett. 2001 Oct;506(2):149-56

Term ID

GO:0003924

Name

GTPase activity

Namespace

molecular_function

Definition

Catalysis of the reaction: GTP + H2O = GDP + phosphate.

Synonyms

20 synonym(s)

ARF small monomeric GTPase activity
dynamin GTPase activity
heterotrimeric G-protein GTPase activity
heterotrimeric G-protein GTPase, alpha-subunit
heterotrimeric G-protein GTPase, beta-subunit
heterotrimeric G-protein GTPase, gamma-subunit
hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
protein-synthesizing GTPase activity
protein-synthesizing GTPase activity, elongation
protein-synthesizing GTPase activity, initiation
protein-synthesizing GTPase activity, termination
Rab small monomeric GTPase activity
Ran small monomeric GTPase activity
Ras small monomeric GTPase activity
RHEB small monomeric GTPase activity
Rho small monomeric GTPase activity
Sar small monomeric GTPase activity
signal-recognition-particle GTPase activity
small monomeric GTPase activity
tubulin GTPase activity

Is-a

1 item(s)

GO:0017111: nucleoside-triphosphatase activity

GO:0004871

[TAS] signal transducer activity

Evidence

References

1 reference(s)

PubMed

MADDEN, K, et al., Annu. Rev. Microbiol. 1998;52:687-744

PMID

Title

Cell polarity and morphogenesis in budding yeast.

Authors

MADDEN, K, et al.

MADDEN, K
SNYDER, M

Citation

Annu. Rev. Microbiol. 1998;52:687-744

Term ID

GO:0004871

Name

signal transducer activity

Namespace

molecular_function

Definition

Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell." [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology

Is-a

1 item(s)

GO:0060089: molecular transducer activity

GO:0005525

[IEA] GTP binding

Evidence

Term ID

GO:0005525

Name

GTP binding

Namespace

molecular_function

Definition

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

Is-a

1 item(s)

GO:0032561: guanyl ribonucleotide binding

Processes

25 process(s)

GO:0000750

[IGI] pheromone-dependent signal transduction involved in conjugation with cellular fusion

Evidence

IGI

References

1 reference(s)

PubMed

MOSKOW, J J, et al., Mol. Cell. Biol. 2000 Oct;20(20):7559-71

PMID

11003652

Title

Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.

Authors

MOSKOW, J J, et al.

MOSKOW, J J
GLADFELTER, A S
LAMSON, R E
PRYCIAK, P M
LEW, D J

Citation

Mol. Cell. Biol. 2000 Oct;20(20):7559-71

Term ID

GO:0000750

Name

pheromone-dependent signal transduction involved in conjugation with cellular fusion

Namespace

biological_process

Definition

A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.

Synonyms

1 synonym(s)

transduction of mating signal

Is-a

2 item(s)

GO:0007186: G-protein coupled receptor protein signaling pathway
GO:0032005: regulation of conjugation with cellular fusion by signal transduction

GO:0000750

[IMP] pheromone-dependent signal transduction involved in conjugation with cellular fusion

Evidence

References

1 reference(s)

PubMed

MOSKOW, J J, et al., Mol. Cell. Biol. 2000 Oct;20(20):7559-71

PMID

11003652

Title

Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae.

Authors

MOSKOW, J J, et al.

MOSKOW, J J
GLADFELTER, A S
LAMSON, R E
PRYCIAK, P M
LEW, D J

Citation

Mol. Cell. Biol. 2000 Oct;20(20):7559-71

Term ID

GO:0000750

Name

pheromone-dependent signal transduction involved in conjugation with cellular fusion

Namespace

biological_process

Definition

Synonyms

1 synonym(s)

transduction of mating signal

Is-a

2 item(s)

GO:0007186: G-protein coupled receptor protein signaling pathway
GO:0032005: regulation of conjugation with cellular fusion by signal transduction

GO:0001403

[IMP] invasive growth in response to glucose limitation

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0001403

Name

invasive growth in response to glucose limitation

Namespace

biological_process

Definition

A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.

Synonyms

1 synonym(s)

colony morphology

Is-a

1 item(s)

GO:0070783: growth of unicellular organism as a thread of attached cells

GO:0007010

[RCA] cytoskeleton organization

Evidence

References

1 reference(s)

PubMed

TIAN, Weidong, et al., Genome Biol. 2008;9 Suppl 1:S7

PMID

Title

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.

Authors

TIAN, Weidong, et al.

TIAN, Weidong
ZHANG, Lan V
TAşAN, Murat
GIBBONS, Francis D
KING, Oliver D
PARK, Julie
WUNDERLICH, Zeba
CHERRY, J Michael
ROTH, Frederick P

Citation

Genome Biol. 2008;9 Suppl 1:S7

Term ID

GO:0007010

Name

cytoskeleton organization

Namespace

biological_process

Definition

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Synonyms

4 synonym(s)

cytoskeletal organization and biogenesis (GOC:mah)
cytoskeletal regulator activity
cytoskeleton organisation (GOC:curators)
cytoskeleton organization and biogenesis (GOC:mah)

Is-a

1 item(s)

GO:0006996: organelle organization

GO:0007015

[RCA] actin filament organization

Evidence

References

1 reference(s)

PubMed

TIAN, Weidong, et al., Genome Biol. 2008;9 Suppl 1:S7

PMID

Title

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.

Authors

TIAN, Weidong, et al.

TIAN, Weidong
ZHANG, Lan V
TAşAN, Murat
GIBBONS, Francis D
KING, Oliver D
PARK, Julie
WUNDERLICH, Zeba
CHERRY, J Michael
ROTH, Frederick P

Citation

Genome Biol. 2008;9 Suppl 1:S7

Term ID

GO:0007015

Name

actin filament organization

Namespace

biological_process

Definition

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.

Synonyms

2 synonym(s)

actin filament organisation (GOC:curators)
regulation of actin filament localization

Is-a

1 item(s)

GO:0030036: actin cytoskeleton organization

GO:0007049

[IEA] cell cycle

Evidence

Term ID

GO:0007049

Name

cell cycle

Namespace

biological_process

Definition

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

Synonyms

1 synonym(s)

cell-division cycle

Is-a

1 item(s)

GO:0009987: cellular process

GO:0007096

[IMP] regulation of exit from mitosis

Evidence

References

1 reference(s)

PubMed

HöFKEN, Thomas, et al., EMBO J. 2002 Sep;21(18):4851-62

PMID

12234925

Title

A role for cell polarity proteins in mitotic exit.

Authors

HöFKEN, Thomas, et al.

HöFKEN, Thomas
SCHIEBEL, Elmar

Citation

EMBO J. 2002 Sep;21(18):4851-62

Term ID

GO:0007096

Name

regulation of exit from mitosis

Namespace

biological_process

Definition

Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.

Is-a

2 item(s)

GO:0007346: regulation of mitotic cell cycle
GO:0010564: regulation of cell cycle process

GO:0007118

[IMP] budding cell apical bud growth

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0007118

Name

budding cell apical bud growth

Namespace

biological_process

Definition

Growth at the tip of a bud, in a cell that reproduces by budding.

Synonyms

1 synonym(s)

apical bud growth

Is-a

1 item(s)

GO:0007117: budding cell bud growth

GO:0007119

[IMP] budding cell isotropic bud growth

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0007119

Name

budding cell isotropic bud growth

Namespace

biological_process

Definition

Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.

Synonyms

1 synonym(s)

isotropic bud growth

Is-a

1 item(s)

GO:0007117: budding cell bud growth

GO:0007124

[IMP] pseudohyphal growth

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0007124

Name

pseudohyphal growth

Namespace

biological_process

Definition

A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.

Is-a

2 item(s)

GO:0016049: cell growth
GO:0070783: growth of unicellular organism as a thread of attached cells

GO:0007264

[IEA] small GTPase mediated signal transduction

Evidence

Term ID

GO:0007264

Name

small GTPase mediated signal transduction

Namespace

biological_process

Definition

Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.

Synonyms

1 synonym(s)

small GTPase-mediated signal transduction

Is-a

1 item(s)

GO:0035556: intracellular signal transduction

GO:0007264

[RCA] small GTPase mediated signal transduction

Evidence

Term ID

GO:0007264

Name

small GTPase mediated signal transduction

Namespace

biological_process

Definition

Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.

Synonyms

1 synonym(s)

small GTPase-mediated signal transduction

Is-a

1 item(s)

GO:0035556: intracellular signal transduction

GO:0007266

[TAS] Rho protein signal transduction

Evidence

References

1 reference(s)

PubMed

MADDEN, K, et al., Annu. Rev. Microbiol. 1998;52:687-744

PMID

Title

Cell polarity and morphogenesis in budding yeast.

Authors

MADDEN, K, et al.

MADDEN, K
SNYDER, M

Citation

Annu. Rev. Microbiol. 1998;52:687-744

Term ID

GO:0007266

Name

Rho protein signal transduction

Namespace

biological_process

Definition

A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.

Synonyms

1 synonym(s)

Rho mediated signal transduction

Is-a

1 item(s)

GO:0007265: Ras protein signal transduction

GO:0009966

[RCA] regulation of signal transduction

Evidence

Term ID

GO:0009966

Name

regulation of signal transduction

Namespace

biological_process

Definition

Any process that modulates the frequency, rate or extent of signal transduction.

Is-a

2 item(s)

GO:0010646: regulation of cell communication
GO:0023051: regulation of signaling process

GO:0019236

[IEA] response to pheromone

Evidence

Term ID

GO:0019236

Name

response to pheromone

Namespace

biological_process

Definition

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.

Synonyms

1 synonym(s)

pheromone response

Is-a

1 item(s)

GO:0010033: response to organic substance

GO:0019953

[RCA] sexual reproduction

Evidence

Term ID

GO:0019953

Name

sexual reproduction

Namespace

biological_process

Definition

The regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.

Is-a

1 item(s)

GO:0000003: reproduction

GO:0030010

[TAS] establishment of cell polarity

Evidence

References

1 reference(s)

PubMed

MADDEN, K, et al., Annu. Rev. Microbiol. 1998;52:687-744

PMID

Title

Cell polarity and morphogenesis in budding yeast.

Authors

MADDEN, K, et al.

MADDEN, K
SNYDER, M

Citation

Annu. Rev. Microbiol. 1998;52:687-744

Term ID

GO:0030010

Name

establishment of cell polarity

Namespace

biological_process

Definition

The specification and formation of anisotropic intracellular organization or cell growth patterns.

Synonyms

2 synonym(s)

bud site selection/establishment of cell polarity
cell polarization

Is-a

1 item(s)

GO:0007163: establishment or maintenance of cell polarity

GO:0030029

[RCA] actin filament-based process

Evidence

References

1 reference(s)

PubMed

TIAN, Weidong, et al., Genome Biol. 2008;9 Suppl 1:S7

PMID

Title

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.

Authors

TIAN, Weidong, et al.

TIAN, Weidong
ZHANG, Lan V
TAşAN, Murat
GIBBONS, Francis D
KING, Oliver D
PARK, Julie
WUNDERLICH, Zeba
CHERRY, J Michael
ROTH, Frederick P

Citation

Genome Biol. 2008;9 Suppl 1:S7

Term ID

GO:0030029

Name

actin filament-based process

Namespace

biological_process

Definition

Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.

Synonyms

1 synonym(s)

microfilament-based process

Is-a

1 item(s)

GO:0009987: cellular process

GO:0030036

[RCA] actin cytoskeleton organization

Evidence

References

1 reference(s)

PubMed

TIAN, Weidong, et al., Genome Biol. 2008;9 Suppl 1:S7

PMID

Title

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.

Authors

TIAN, Weidong, et al.

TIAN, Weidong
ZHANG, Lan V
TAşAN, Murat
GIBBONS, Francis D
KING, Oliver D
PARK, Julie
WUNDERLICH, Zeba
CHERRY, J Michael
ROTH, Frederick P

Citation

Genome Biol. 2008;9 Suppl 1:S7

Term ID

GO:0030036

Name

actin cytoskeleton organization

Namespace

biological_process

Definition

Synonyms

3 synonym(s)

actin cytoskeleton organisation (GOC:curators)
actin cytoskeleton organization and biogenesis (GOC:mah)
actin modulating activity

Is-a

2 item(s)

GO:0007010: cytoskeleton organization
GO:0030029: actin filament-based process

GO:0030447

[RCA] filamentous growth

Evidence

Term ID

GO:0030447

Name

filamentous growth

Namespace

biological_process

Definition

The process by which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.

Is-a

1 item(s)

GO:0040007: growth

GO:0031384

[IMP] regulation of initiation of mating projection growth

Evidence

References

1 reference(s)

PubMed

BIDLINGMAIER, Scott, et al., J. Cell Biol. 2004 Jan;164(2):207-18

PMID

14734532

Title

Regulation of polarized growth initiation and termination cycles by the polarisome and Cdc42 regulators.

Authors

BIDLINGMAIER, Scott, et al.

BIDLINGMAIER, Scott
SNYDER, Michael

Citation

J. Cell Biol. 2004 Jan;164(2):207-18

Term ID

GO:0031384

Name

regulation of initiation of mating projection growth

Namespace

biological_process

Definition

Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.

Is-a

1 item(s)

GO:0031383: regulation of mating projection assembly

GO:0032889

[IMP] regulation of vacuole fusion, non-autophagic

Evidence

References

1 reference(s)

PubMed

EITZEN, G, et al., EMBO J. 2001 Oct;20(20):5650-6

PMID

11598008

Title

Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking.

Authors

EITZEN, G, et al.

EITZEN, G
THORNGREN, N
WICKNER, W

Citation

EMBO J. 2001 Oct;20(20):5650-6

Term ID

GO:0032889

Name

regulation of vacuole fusion, non-autophagic

Namespace

biological_process

Definition

Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.

Is-a

1 item(s)

GO:0044088: regulation of vacuole organization

GO:0045921

[IGI] positive regulation of exocytosis

Evidence

IGI

References

1 reference(s)

PubMed

WU, Hao, et al., Mol. Biol. Cell 2010 Feb;21(3):430-42

PMID

19955214

Title

The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis.

Authors

WU, Hao, et al.

WU, Hao
TURNER, Courtney
GARDNER, Jimmy
TEMPLE, Brenda
BRENNWALD, Patrick

Citation

Mol. Biol. Cell 2010 Feb;21(3):430-42

Term ID

GO:0045921

Name

positive regulation of exocytosis

Namespace

biological_process

Definition

Any process that activates or increases the frequency, rate or extent of exocytosis.

Synonyms

5 synonym(s)

activation of exocytosis
stimulation of exocytosis
up regulation of exocytosis
up-regulation of exocytosis
upregulation of exocytosis

Is-a

3 item(s)

GO:0017157: regulation of exocytosis
GO:0048522: positive regulation of cellular process
GO:0051047: positive regulation of secretion

GO:0045921

[IPI] positive regulation of exocytosis

Evidence

IPI

References

1 reference(s)

PubMed

WU, Hao, et al., Mol. Biol. Cell 2010 Feb;21(3):430-42

PMID

19955214

Title

The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis.

Authors

WU, Hao, et al.

WU, Hao
TURNER, Courtney
GARDNER, Jimmy
TEMPLE, Brenda
BRENNWALD, Patrick

Citation

Mol. Biol. Cell 2010 Feb;21(3):430-42

Term ID

GO:0045921

Name

positive regulation of exocytosis

Namespace

biological_process

Definition

Any process that activates or increases the frequency, rate or extent of exocytosis.

Synonyms

5 synonym(s)

activation of exocytosis
stimulation of exocytosis
up regulation of exocytosis
up-regulation of exocytosis
upregulation of exocytosis

Is-a

3 item(s)

GO:0017157: regulation of exocytosis
GO:0048522: positive regulation of cellular process
GO:0051047: positive regulation of secretion

GO:0051301

[IEA] cell division

Evidence

Term ID

GO:0051301

Name

cell division

Namespace

biological_process

Definition

The process resulting in the physical partitioning and separation of a cell into daughter cells.

Is-a

1 item(s)

GO:0009987: cellular process

Components

9 component(s)

GO:0001950

[RCA] plasma membrane enriched fraction

Evidence

References

1 reference(s)

PubMed

TIAN, Weidong, et al., Genome Biol. 2008;9 Suppl 1:S7

PMID

Title

Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function.

Authors

TIAN, Weidong, et al.

TIAN, Weidong
ZHANG, Lan V
TAşAN, Murat
GIBBONS, Francis D
KING, Oliver D
PARK, Julie
WUNDERLICH, Zeba
CHERRY, J Michael
ROTH, Frederick P

Citation

Genome Biol. 2008;9 Suppl 1:S7

Term ID

GO:0001950

Name

plasma membrane enriched fraction

Namespace

cellular_component

Definition

The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.

Synonyms

1 synonym(s)

PME fraction (GOC:mah)

Is-a

1 item(s)

GO:0000267: cell fraction

GO:0005622

[IEA] intracellular

Evidence

Term ID

GO:0005622

Name

intracellular

Namespace

cellular_component

Definition

The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology

Synonyms

4 synonym(s)

internal to cell
nucleocytoplasm (GOC:mah)
protoplasm
protoplast (GOC:mah)

Is-a

1 item(s)

GO:0044464: cell part

GO:0005625

[IDA] soluble fraction

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0005625

Name

soluble fraction

Namespace

cellular_component

Definition

That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.

Synonyms

1 synonym(s)

soluble

Is-a

1 item(s)

GO:0000267: cell fraction

GO:0005886

[IDA] plasma membrane

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID

Title

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.

Authors

JOHNSON, D I

JOHNSON, D I

Citation

Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

Term ID

GO:0005886

Name

plasma membrane

Namespace

cellular_component

Definition

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Synonyms

7 synonym(s)

bacterial inner membrane
cell membrane
cytoplasmic membrane
inner endospore membrane
juxtamembrane
plasma membrane lipid bilayer (GOC:mah)
plasmalemma

Is-a

1 item(s)

GO:0016020: membrane

GO:0005886

[IEA] plasma membrane

Evidence

Term ID

GO:0005886

Name

plasma membrane

Namespace

cellular_component

Definition

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Synonyms

7 synonym(s)

bacterial inner membrane
cell membrane
cytoplasmic membrane
inner endospore membrane
juxtamembrane
plasma membrane lipid bilayer (GOC:mah)
plasmalemma

Is-a

1 item(s)

GO:0016020: membrane

GO:0005934

[TAS] cellular bud tip

Evidence

References

1 reference(s)

PubMed

MADDEN, K, et al., Annu. Rev. Microbiol. 1998;52:687-744

PMID

Title

Cell polarity and morphogenesis in budding yeast.

Authors

MADDEN, K, et al.

MADDEN, K
SNYDER, M

Citation

Annu. Rev. Microbiol. 1998;52:687-744

Term ID

GO:0005934

Name

cellular bud tip

Namespace

cellular_component

Definition

The end of a cellular bud distal to the site of attachment to the mother cell.

Is-a

1 item(s)

GO:0030427: site of polarized growth

GO:0005935

[TAS] cellular bud neck

Evidence

References

1 reference(s)

PubMed

MADDEN, K, et al., Annu. Rev. Microbiol. 1998;52:687-744

PMID

Title

Cell polarity and morphogenesis in budding yeast.

Authors

MADDEN, K, et al.

MADDEN, K
SNYDER, M

Citation

Annu. Rev. Microbiol. 1998;52:687-744

Term ID

GO:0005935

Name

cellular bud neck

Namespace

cellular_component

Definition

The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.

Is-a

1 item(s)

GO:0030427: site of polarized growth

GO:0016020

[IEA] membrane

Evidence

Term ID

GO:0016020

Name

membrane

Namespace

cellular_component

Definition

Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

Is-a

1 item(s)

GO:0044464: cell part

GO:0043332

[IDA] mating projection tip

Evidence

References

1 reference(s)

PubMed

JOHNSON, D I, Microbiol. Mol. Biol. Rev. 1999 Mar;63(1):54-105

PMID